Frequently Asked Questions

by Kan Lu
  1. What are the ingredients in Nano.Silver Acne Gel?
The ingredients include silver nanoparticles(AgNP), Salicylic acid, Carboxymethylcellulose, propylene glycol and aqua.

 

  1. What are those ingredients used for?
Salicylic acid is a well-known ingredient approved by FDA for acne treatment. It helps unclog pores to resolve and prevent lesions, however it does not have effect on sebum production and does not kill bacteria. On the other hand, AgNP has antimicrobial and anti-inflammatory effects. Carboxymethylcellulose and propylene glycol are used to make an amorphous hydrogel which gently re-hydrates necrotic tissue, facilitating debridement, which promotes the healing process. As dead tissue not only inhibit healthy new tissue but also can cause infection.
Propylene glycol is an alcohol. It can be used as preservative due to its antifungal and antimicrobial property. It also helps active ingredient penetrate skin.

 

  1. What does Nano.Silver Acne Gel make difference from other

acne gel(cream) available on market?

Salicylic acid and benzoyl peroxide are widely used ingredient for OTC acne treatment. Salicylic acid can penetrate into pores to unblock oil and prevent further breakout lesions. Benzoyl peroxide is another effective ingredient against acne. It can kill bacteria, while exfoliating the pores at the same time,

 

 Acne cream(gel) found in over-the-counter have high concentrations of salicylic acid or benzoyl peroxide. They can cause most side effect of drying and irritation. Benzoyl peroxide may bleach hair and colored fabric.  The formulation strategy of Nano.Silver Acne Gel is using low dose salicylic acid (0.5%) with AgNP prepared by our most advanced nanotechnology.  AgNP were well known for its activity against nearly 150 strains of bacteria as well as common fungi and viruses with no antibiotic resistance. AgNP also has anti-inflammatory effect and the ability to improve the healing process significantly. The proposed mechanism is that AgNp facilitate the proliferation and migration of keratinocytes, reduce the formation of collagen by fibroblasts and modulate the number of cytokines produced (Materials 2013 6,2295-2350). The low dose salicylic acid minimizes the side effect of irritation…..

 

  1. Why does AgNP have antimicrobial property?

The silver nanoparticles(AgNP) can get attached to the cell membrane and penetrate inside the bacteria. The nanoparticles preferably attack the respiratory chain and finally cause cell death. As the size of particle decrease, their surface area increase leading to an increase in their antibacterial efficiency increases exponentially due to their smaller size.

 

  1. What causes acne?

Acne is a common skin disease. Blackheads, whiteheads and pimples are all caused by excess oil released by sebaceous glands. Once the skin pores are clogged by the excess oil, they may become whitehead or blackhead depending on how many dead skin cell cover the follicle opening.  The clogged pores also are bleeding ground for bacteria growth. If the bacteria cause to inflammation, then severe acne (acne vulgaris) will be formed. A lot of research has been done on what causes acne but there is no final answer. It can be hormone changes such as those during the teenage years, greasy food or dirty skin, but no one knows.

 

  1. How do I apply Nano.silver Acne Gel?

Wash and dry the area to be treated. Apply with fingertip a thin layer of gel to cover the entire affected area. Gently rub the gel in until it is evenly distributed. Do not get the gel into the eyes.  If this is happened, rinse them out with water immediately.

 

  1. Does Nano.Silver Acne Gel have any side effects?

As lowest dose of salicylic acid was used in the formulation of the gel. Most common side effects such as drying and irritation are minimized.

 

  1. How long does it take to see the result?

You may see improvement in few days. If your acne is severe (the bacteria cause to inflammation), it might take few weeks to see the visible improvement. It all depends on acne skin condition. It will vary from person to person.

 

  1. How to properly store the gel?

Store the gel at room temperature, away from heat. Keep out of reach of children.

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